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Silvia Smaldone Selected Research

Congenital contractural arachnodactyly

5/2016Fibrillin microfibrils in bone physiology.
6/2015Abnormal Activation of BMP Signaling Causes Myopathy in Fbn2 Null Mice.
10/2010Extracellular microfibrils control osteoblast-supported osteoclastogenesis by restricting TGF{beta} stimulation of RANKL production.

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Silvia Smaldone Research Topics

Disease

10Marfan Syndrome (Marfan's Syndrome)
01/2022 - 02/2009
3Congenital contractural arachnodactyly
05/2016 - 10/2010
3Aortic Aneurysm (Aneurysm, Aortic)
04/2015 - 02/2009
2Bone Resorption
01/2016 - 10/2010
2Aneurysm (Aneurysms)
04/2015 - 12/2010
2Fibrosis (Cirrhosis)
03/2011 - 12/2010
1Hypertrophy
06/2015
1Contracture
06/2015
1Muscular Dystrophies (Muscular Dystrophy)
06/2015
1Thoracic Aortic Aneurysm
04/2015
1Perinatal Death
08/2012
1Disease Progression
03/2011
1Metabolic Bone Diseases (Osteopenia)
12/2010
1Vascular Diseases (Vascular Disease)
12/2010
1Stiff Skin Syndrome
12/2010

Drug/Important Bio-Agent (IBA)

8Fibrillin-1IBA
01/2022 - 02/2009
3FibrillinsIBA
05/2016 - 10/2010
2Extracellular Matrix ProteinsIBA
01/2016 - 02/2009
2Fibrillin-2IBA
06/2015 - 10/2010
2Losartan (Cozaar)FDA LinkGeneric
04/2015 - 12/2010
1Proteins (Proteins, Gene)FDA Link
01/2022
1Myosins (Myosin)IBA
06/2015
1Myosin Heavy Chains (Myosin Heavy Chain)IBA
06/2015
1AngiotensinsIBA
04/2015
1Transforming Growth Factors (Transforming Growth Factor)IBA
04/2015
1Smad Proteins (Mothers Against Decapentaplegic Homolog)IBA
04/2015
1Neutralizing AntibodiesIBA
04/2015
1CollagenIBA
03/2011
1Reactive Oxygen Species (Oxygen Radicals)IBA
03/2011
1Alendronate (Alendronate Sodium)FDA LinkGeneric
12/2010
1IntegrinsIBA
12/2010
1Transforming Growth Factor beta (TGF-beta)IBA
02/2009
1p38 Mitogen-Activated Protein KinasesIBA
02/2009

Therapy/Procedure

2Therapeutics
04/2015 - 12/2010